Lara Vigneron


Tel : +32-4-3662642 (office)
        +32-4-3662984 (fax)
Email :
Bureau: Institut Montefiore, II96 (Parking 32)


Department of Electrical Engineering and Computer Science (Institut Montefiore)
Signal Processing Group
Université de Liège
Sart-Tilman, B28
B-4000 Liège, BELGIUM


The main goal of brain surgery is to remove as much as possible of lesional tissues, while avoiding contacts with eloquent areas. Surgery is planned on the basis of preoperative images of multiple modalities, such as CT, sMRI, fMRI. It is generally performed using an image-guided navigation system that relates the 3D preoperative images to patient coordinates. However, throughout surgery, the brain deforms, mostly as a result of surgical acts, such as retraction and resection. As surgery progresses, preoperative images become progressively less representative of the brain, and navigation accuracy decreases. My work is to evaluate brain deformations from reduced-quality intraoperative images acquired at several critical points during surgery, and to update in real-time during surgery all high-quality preoperative images using a nonrigid registration technique based on a biomechanical model of the brain. My research focuses on the enhancement of this biomechanical model,for the modelling of brain incision and tissues resection occurring during operation.


FEM/XFEM-Based Modeling of Brain Shift, Resection, and Retraction for Image-Guided Surgery, 26 February 2009
Thesis manuscript
Thesis defense


Lara M. Vigneron, Roman C. Boman, Jean-Philippe Ponthot, Pierre A. Robe, Simon K. Warfield, and Jacques G.Verly. Enhanced FEM-based Modeling of Brain Shift Deformation in Image-Guided Neurosurgery. Journal of Computational and Applied Mathematics.In press, 2009

Lara M. Vigneron, Marc P. Duflot, Pierre A. Robe, Simon K. Warfield, and Jacques G.Verly. 2D XFEM-based Modeling of Retraction and Successive Resections for Preoperative Image Update. Computer Aided Surgery, 2009

Lara M. Vigneron, Romain C. Boman, Pierre A. Robe, Simon K. Warfield, Jacques G. Verly. 3D FEM/XFEM-based Biomechanical Brain Modeling for Preoperative Image Update. MICCAI Conference, Workshop on Computational Biomechanics for Medicine II, pp. 33-42, 2007

Lara M. Vigneron, Pierre A. Robe, Simon K. Warfield, and Jacques G. Verly. XFEM-based modeling of successive resections for preoperative image updating. In Proceedings of the Medical Imaging: Visualization, Image-Guided Procedures and Display, SPIE, Vol. 5367, pp. 735-746, (San Diego, USA), 2006

Lara M. Vigneron, Jacques G. Verly, Simon K. Warfield. On Extended Finite Element Method (XFEM) for Modelling of Organ Deformations Associated with Surgical Cuts. Proceedings of the International Symposium on Medical Simulation 2004, pp 134-143 (Cambridge, MA, USA), 2004

Lara M. Vigneron, Jacques G. Verly, Simon K. Warfield. Modelling Surgical Cuts, Retractions, and Resections via Extended Finite Element Method. Proceeding of the 7th International Conference on Medical Image Computing and Computer Assisted Intervention, Vol. 3217 (2), pp 311-318 (Saint-Malo, France)

Lara M. Vigneron, Jacques G. Verly, Pierre A. Robe, and Simon K. Warfield. New Approach for Efficient Prediction of Brain Deformation and Updating of Preoperative Images Based on the Extended Finite Element Method. Proceedings of the 5th Interventional MRI Symposium (Cambridge, MA, USA), 2004

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