Teaching 2013-2014

• What if I have additional questions?
• Consult Kristel Van Steen (kristel.vansteen@ulg.ac.be) before or after class or by e-mail. In order for the mail not to get lost, please mention "genetic epidemiology" in the subject title
• Course schedule / Location
• When does the course take place?
• Where does the course take place?
• Scoring
• Partitioning of the final score (updated 24 March 2014)

• Course notes:
• Relevant questions in genetic epidemiology
• Supplement 1: Genetics revisited
• Supplement 2: The new epidemiologist
• Supplement 3: Life is complicated
• Course workshop papers:
• Series of Lancet Papers serving as background information
• Project assignments:
• GWAs
• Adding complexity to GWAs
• Preparatory notes for next class:
• Supplement 4: Highlights on genetics + Aggregation and Segregation (courses.washington.edu/b516)
• Preparing for the exam:
• Guiding questions to prepare oral exam

• Course notes:
• ~ see class 1
• Supplement 1: Highlights on non-parametric linkage (courses.washington.edu/b516)
• Basic population genetics
• Supplement 2: Highlights on population genetics concepts (courses.washington.edu/b516)
• Supplement 3: Estimating kinship in admixed populations
• Preparatory notes for next class:
• Downloading instructions R and Bioconductor: Follow this link
• Information on using R:
• Part 1: R manuals
• Part 2: Basic Commands !!!
• Part 3: An introduction to R
• Part 4: Advanced
• Part 5: A few illustrative examples in R

• Course notes:
• ~ see class 2
• Genetic association studies
• Supplement 1: Highlights on association testing (courses.washington.edu/b516)
• Course workshop papers:
• The pursuit of genome-wide association studies: where are we now?
• Progress and promise of genome-wide association studies for human complex trait genetics
• The promise and limitations of genome-wide association studies
• Preparatory notes for next class:
• Supplement 1: Simple regression revisited

• Course notes:
• ~ see class 3
• Genetic association studies
• Supplement 1: Highlights on association testing (courses.washington.edu/b516)

• Current = 2010
• Current = 2011
• Current = 2012

• Course notes:
• Useful links and sites
• GWAs: from theory to practice
• Perspective from a statistician
• Perspective from a bioinformatician
• Handy guide for data quality control in practice
• GWAs: a tour in R
• R is not the only environment ... A-Z list of genetic analysis software
• A toy example in R
• SNPassoc in R
• SNPassoc code (cut and paste) - Tinn-R
• A quick guide to large-scale genomic data mining
• Introduction to GenABEL

• Course notes:
• Family-based Genetic association studies
• In-class FBAT try-outs:
• SNPassoc / FBAT examples (R code included)
• FBAT software
• FBAT tour
• FBAT manual

• Course notes:
• ~ see class 6
• Genomewide Association Interaction Studies
• A side note:
• Getting an identity crisis?
• Flagship pilots
• ITFoM
• Preparing for the exam:
• Guiding questions

• Guest lecture (Hilde Peeters - KUL)
• Research Seminar Genetic Epidemiology
• Discussions + Preparing for the exam:
• Guiding questions