Samuel Hiard

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Who am I?

Researcher since the first september 2005, I'm specialising in the bioinformatic field and in supervised learning
I'm a member of the bioinformatic team in the Systems and Modeling research unit (see also Louis Wehenkel's home page)

I designed PREDetector, which is a software used to detect the regulatory areas of bacterias, and I improved Patrocles, a website allowing to analyze the genetic mutations affecting the mechanism of regulation by miRNA (whether it affects the target, the host gene of the miRNA or the machinery of regulation)

My thesis relates to the improvement of the Ranking by Pairwise Comparison (RPC) technique. With this technique, one is confronted to a computational complexity of order N², and my goal is to reduce this complexity to an order N, by selecting the most optimal possible subset of N base classifiers, while preserving an acceptable reliability of ranking.

How to reach me?

Montefiore Institute (B28)
Grande Traverse, 10
4000 Liege
Belgium

Systems and Modeling
Office II/99

Phone: (+32) 4 366 2641
Mail: Internal box 15
Email: S.Hiard@ulg.ac.be

Information for students

Publications

2011
Using Class-probability Models instead of Hard Classifiers as Base Learners in the Ranking by Pairwise Comparison Algorithm  
Samuel Hiard, Louis Wehenkel
ICMLC 2011 3rd International Conference on Machine Learning and Computing, Volume 1, page 218--222 - feb 2011
 
2009
Patrocles: a database of polymorphic miRNA-mediated gene regulation in vertebrates  
Samuel Hiard, Carole Charlier, Wouter Coppieters, Michel Georges, Denis Baurain
Nucleid Acid Research, Volume 38, page D640--D665 - nov 2009
 
2007
Predetector: a new tool to identify regulatory elements in bacterial genomes   hiard2007-PREDetector.pdf
Samuel Hiard, Raphaël Marée, Séverine Colson, Paul A. Hoskinson, Fritz Titgemeyer, Gilles P. van Weeze, Bernard Joris, Louis Wehenkel, Sébastien Rigali
Biochemical and Biophysical Research Communications, Volume 357, Number 4, page 861-864 - June 2007
 
2006
Polymorphic miRNA-target interactions  
M. Georges, A. Clop, F. Marcq, H. Takeda, D. Pirottin, X. Tordoir, Samuel Hiard, B. Bibé, J. Bouix, F. Caiment, F. Eychenne, C. Larzul, E. Laville, F. Meish, D. Milenkovic, J. Tobin, C. Charlier
Regulatory RNAs - Cold Spring Harbor Symposium on Quantitative Biology, Cold Spring Harbor Laboratory, Volume 71 - 2006
The callipyge mutation enhances bidirectional long-range DLK1-GTL2 intergenic transcription in cis  
H. Takeda, F. Caiment, M. Smit, Samuel Hiard, X. Tordoir, N. Cockett, M. Georges, C. Charlier
Proceedings of the National Academy of Sciences USA, Volume 103, page 8119-8124 - 2006

My accomplishments as a researcher

Patrocles

Patrocles


This website analyzes the genetic mutations affecting the regulation by miRNA in the eukaryotes.
Only some species are currently considered, but new species are added regularly.

Xavier Tordoir designed the first version of this site
Denis Baurain continues the development

For more information, consult the web page dedicated to this work
PREDetector

Predetector


This program allows to dertermine which genes are regulated by the cis sequences (adn)
given in argument for the chosen bacteria.

For more information, consult the web page dedicated to this work

My accomplishments as a student

Rush Hour

Rush Hour


My final dissertation was about the exhaustive search of all possible configurations
for the Rush Hour puzzle game.

For more information, consult the web page dedicated to this work

Useful Links

The database to use for the Applied Inductive Learning course: Omib.zip

http://www.montefiore.ulg.ac.be/~lwh : Louis Wehenkel's personal home page
http://www.pepite.be : PEPITe S.A. website
http://www.ulg.ac.be : ULg website
http://www.giga.ulg.ac.be : GIGA website
http://www.montefiore.ulg.ac.be : Montefiore institute website
http://www.montefiore.ulg.ac.be/services/stochastic : Research unit website
http://www.kuleuven.be/biomagnet/ : IAP BioMAGNet website
http://sites.uclouvain.be/dysco/ : IAP DYSCO website
Person in charge: Samuel HIARD
Email: S.Hiard@ulg.ac.be