T-Trees

A novel tree-based approach for Genome-Wide Association Studies

Supplementary data

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6	Best: rs3094050 (2)	Gene	30.45-30.47Mb	MAF	HWE(case)	HWE(cont)	p-value	imp.	rank
	rs3129818		30450945	0.1719	0.04539	0.5346	5.06e-29	0.00026	193
	rs3094050		30466570	0.1722	0.03375	0.486	1.202e-29	0.00031	174
6	Best: rs6930444 (3)	Gene	30.87-30.90Mb	MAF	HWE(case)	HWE(cont)	p-value	imp.	rank
	rs6930444		30871611	0.03002	0.7972	0.6268	2.446e-14	0.00039	148
	rs10947096		30873874	0.1712	0.1098	0.8838	9.17e-13	0.00034	168
	rs12215119	LINC00243 NCBI Gene Pubmed Genecard	30903307	0.1383	0.002861	1	5.264e-17	0.00033	169
6	Best: rs3130544 (4)	Gene	31.17-31.25Mb	MAF	HWE(case)	HWE(cont)	p-value	imp.	rank
	rs3130544		31166319	0.1876	0.06197	0.2747	3.79e-35	0.00089	84
	rs1265048	C6orf15 NCBI Gene Pubmed Genecard PSORS1C1 NCBI Gene Pubmed Genecard	31189388	0.3349	0.2459	0.8649	6.353e-08	0.00037	158
	rs3130564	PSORS1C1 NCBI Gene Pubmed Genecard	31209653	0.289	0.03177	0.411	2.016e-20	0.00026	197
	rs887464	PSORS1C3 NCBI Gene Pubmed Genecard	31253899	0.4817	0.0009019	0.007807	5.789e-31	0.00063	105
6	Best: rs3132486 (2)	Gene	31.35-31.35Mb	MAF	HWE(case)	HWE(cont)	p-value	imp.	rank
	rs3132486		31351149	0.3991	0.2917	0.2823	3.146e-48	0.0012	65
	rs2524067		31353800	0.2173	0.5411	0.6106	2.545e-36	0.00035	165
6	Best: rs9273363 (179)	Gene	31.44-33.06Mb	MAF	HWE(case)	HWE(cont)	p-value	imp.	rank
	rs2596477		31435702	0.1534	0.001023	0.1757	4.967e-10	0.0003	177
	rs2523537		31443686	0.144	0.002837	0.2043	1.062e-28	0.00058	118
	rs2596437		31447065	0.1436	0.5939	0.08891	8.016e-33	0.00038	154
	rs12178292		31448412	0.3877	0.2634	0.7076	2.32e-42	0.00059	112
	rs2523638		31452252	0.3985	0.1318	0.8533	3.324e-43	0.00056	119
	rs3957111		31452469	0.1121	0.5949	0.01456	0.03086	0.00028	184
	rs2596571		31456001	0.2186	0.8618	0.07227	2.362e-40	0.00035	163
	rs2523485		31459014	0.1276	0.4506	0.5374	4.505e-32	0.00027	189
	rs9266774		31460859	0.1306	0.1283	0.6023	4.351e-32	0.00078	95
	rs9266775		31461396	0.1302	0.1091	0.6021	1.117e-31	0.00051	125
	rs2395485		31467627	0.2818	0.006432	0.1348	7.201e-20	0.0004	143
	rs2596517		31468074	0.1441	0.6927	0.2329	2.669e-32	0.00063	106
	rs2244579		31544618	0.1985	0.4432	0.04135	3.289e-18	0.00066	102
	rs2516516		31551549	0.1216	0.5206	0.08618	5.43e-31	0.00031	175
	rs2248459		31554689	0.4012	0.004679	0.7733	1.821e-60	0.0013	59
	rs2248462		31554775	0.1889	0.01696	0.2056	3.359e-28	0.00059	114
	rs2248617		31556512	0.4025	0.01352	0.9346	9.396e-60	0.00096	81
	rs3099844		31556955	0.1851	0.06537	0.8192	1.042e-44	0.0011	70
	rs2516422		31557248	0.1887	0.017	0.224	5.558e-28	0.00032	170
	rs2523467		31565557	0.283	0.006474	0.22	2.032e-21	0.00059	115
	rs2395034		31568122	0.1915	0.01435	0.3464	2.934e-28	0.00055	120
	rs3131631		31592662	0.2046	0.7221	0.7645	5.108e-31	0.00069	100
	rs1799964	LOC100287329 NCBI Gene Pubmed Genecard LTA NCBI Gene Pubmed Genecard TNF NCBI Gene Pubmed Genecard	31650287	0.2266	0.9058	1	8.122e-08	0.00028	183
	rs1052248	LST1 NCBI Gene Pubmed Genecard NCR3 NCBI Gene Pubmed Genecard	31664560	0.254	0.1247	0.3208	0.01177	0.00028	181
	rs9348876		31683255	0.05584	0.4347	1	7.79e-20	0.00084	88
	rs2736177		31694073	0.1027	1	0.2529	1.776e-55	0.0014	54
	rs2736172	PRRC2A NCBI Gene Pubmed Genecard SNORA38 NCBI Gene Pubmed Genecard	31698877	0.3393	0.05876	0.1829	0.02186	0.00034	166
	rs1046089	PRRC2A NCBI Gene Pubmed Genecard	31710946	0.439	0.9639	0.9684	9.476e-77	0.0028	27
	rs760293	BAG6 NCBI Gene Pubmed Genecard	31719756	0.1345	0.6318	0.5645	2.435e-46	0.00043	137
	rs3130048	BAG6 NCBI Gene Pubmed Genecard	31721718	0.3221	0.04842	0.407	8.842e-36	0.00038	150
	rs805301	BAG6 NCBI Gene Pubmed Genecard	31726100	0.4535	0.9271	0.4354	3.056e-75	0.0038	19
	rs805297	APOM NCBI Gene Pubmed Genecard	31730585	0.2887	0.05282	0.3672	0.1899	0.0015	53
	rs9378164		31751501	0.04756	0.3999	0.0538	4.302e-16	0.00036	162
	rs376510	LY6G6C NCBI Gene Pubmed Genecard	31796179	0.07782	0.8129	0.512	4.619e-17	0.00028	180
	rs805294	LY6G6C NCBI Gene Pubmed Genecard	31796196	0.42	0.002321	0.01321	1.199e-63	0.0014	56
	rs707915	MSH5 NCBI Gene Pubmed Genecard MSH5-SAPCD1 NCBI Gene Pubmed Genecard	31818947	0.07734	0.813	0.8672	6.854e-18	0.0004	142
	rs3130484	MSH5 NCBI Gene Pubmed Genecard MSH5-SAPCD1 NCBI Gene Pubmed Genecard	31823861	0.1736	0.06958	1	5.225e-54	0.0012	63
	rs3131379	MSH5 NCBI Gene Pubmed Genecard MSH5-SAPCD1 NCBI Gene Pubmed Genecard	31829012	0.1733	0.03335	0.8673	2.919e-52	0.00064	104
	rs480092	LSM2 NCBI Gene Pubmed Genecard VARS NCBI Gene Pubmed Genecard	31872878	0.1872	0.09503	0.6346	7.362e-16	0.00038	153
	rs2075800	HSPA1L NCBI Gene Pubmed Genecard	31885925	0.3226	0.005868	0.07243	0.002859	0.0011	71
	rs2763979	HSPA1B NCBI Gene Pubmed Genecard	31902571	0.4184	0.1151	0.9678	1.151e-65	0.0036	20
	rs486416	EHMT2 NCBI Gene Pubmed Genecard	31964049	0.3466	0.01792	0.09253	0.04533	0.00091	83
	rs9267673		31991658	0.1032	0.5295	1	1.015e-06	0.00054	121
	rs644045		31991936	0.3658	6.793e-06	0.004705	0.1364	0.00046	135
	rs541862	CFB NCBI Gene Pubmed Genecard	32024930	0.07517	1	0.3237	5.782e-17	0.00048	129
	rs9501161	MIR1236 NCBI Gene Pubmed Genecard RDBP NCBI Gene Pubmed Genecard	32032306	0.07297	0.6819	0.5437	6.884e-06	0.00052	123
	rs406936	SKIV2L NCBI Gene Pubmed Genecard	32041140	0.1035	0.2677	0.3697	5.265e-26	0.00098	78
	rs492899	SKIV2L NCBI Gene Pubmed Genecard	32041497	0.1038	0.03308	0.899	1.809e-23	0.0012	60
	rs3130287	TNXB NCBI Gene Pubmed Genecard	32158522	0.09901	0.724	0.1335	6.602e-81	0.0044	14
	rs1150753	TNXB NCBI Gene Pubmed Genecard	32167845	0.1735	0.0303	0.5551	1.904e-56	0.002	41
	rs1269851	ATF6B NCBI Gene Pubmed Genecard	32200185	0.03877	0.5558	1	3.104e-16	0.00036	161
	rs388629		32213490	0.0407	0.6273	0.1871	2.063e-12	0.00035	164
	rs3130348	AGPAT1 NCBI Gene Pubmed Genecard	32248255	0.2545	0.006254	0.2145	3.329e-11	0.00048	130
	rs3130284	AGPAT1 NCBI Gene Pubmed Genecard	32248465	0.2539	0.004578	0.2549	1.365e-11	0.00042	139
	rs408359	AGPAT1 NCBI Gene Pubmed Genecard	32249861	0.07985	0.7231	0.08281	3.577e-15	0.00084	90
	rs204991	GPSM3 NCBI Gene Pubmed Genecard	32269344	0.2465	0.0003306	0.9124	7.466e-23	0.00026	191
	rs204990	GPSM3 NCBI Gene Pubmed Genecard	32269408	0.2459	0.0003991	1	2.669e-23	0.00026	199
	rs2071278	NOTCH4 NCBI Gene Pubmed Genecard	32273422	0.2062	0.01604	0.537	1.635e-45	0.0016	47
	rs3131294	NOTCH4 NCBI Gene Pubmed Genecard	32288124	0.09146	0.07754	0.1412	2.508e-99	0.0058	10
	rs206015	NOTCH4 NCBI Gene Pubmed Genecard	32290737	0.1126	0.002506	0.8715	4.51e-12	0.00039	147
	rs438475	NOTCH4 NCBI Gene Pubmed Genecard	32294223	0.1385	0.04008	0.4033	1.449e-10	0.00059	113
	rs379464	NOTCH4 NCBI Gene Pubmed Genecard	32294326	0.05936	0.882	0.5111	2.653e-15	0.00088	86
	SNP_A-2064274		32300414	0.0692	1.2e-07	0.004361	1.238e-15	0.00062	109
	rs377763		32307122	0.281	0.000153	0.4077	6.25e-81	0.0042	17
	rs3134926		32308125	0.2676	0.9	0.8242	1.617e-10	0.0011	69
	rs424232		32316302	0.3224	0.02682	0.3574	3.057e-35	0.0016	46
	rs9267954		32321030	0.298	0.01792	0.09683	7.026e-11	0.00029	178
	rs6936204		32325070	0.3393	0.001425	0.0167	4.05e-06	0.0024	34
	rs7767325		32341864	0.2628	0.0004382	0.1874	7.279e-13	0.00046	133
	rs3132928		32341993	0.2625	0.0004382	0.2039	4.149e-13	0.00037	156
	rs3115560		32344120	0.2643	0.0005101	0.1393	7.142e-14	0.00043	138
	rs1265777	C6orf10 NCBI Gene Pubmed Genecard	32381136	0.4203	3.477e-06	0.6425	1.351e-17	0.00027	186
	rs9268230	C6orf10 NCBI Gene Pubmed Genecard	32395545	0.2522	0.07907	0.03595	6.083e-99	0.0061	9
	rs12524063	C6orf10 NCBI Gene Pubmed Genecard	32405288	0.09111	0.2634	0.7459	0.3928	0.0015	51
	rs3132959	C6orf10 NCBI Gene Pubmed Genecard	32406920	0.1644	0.4035	0.03745	1.15e-139	0.0046	13
	rs926591	C6orf10 NCBI Gene Pubmed Genecard	32413668	0.4208	4.271e-06	0.6427	1.377e-17	0.00026	200
	rs3129900	C6orf10 NCBI Gene Pubmed Genecard	32413957	0.1079	1	0.06866	1.227e-119	0.0031	24
	rs9368716	C6orf10 NCBI Gene Pubmed Genecard	32414068	0.4798	0.005963	0.3552	2.446e-05	0.00062	108
	rs910049	C6orf10 NCBI Gene Pubmed Genecard	32423705	0.168	0.06377	0.0001615	2.345e-139	0.0034	23
	rs2894249	C6orf10 NCBI Gene Pubmed Genecard	32433813	0.1611	0.5246	0.3487	1.366e-130	0.0015	52
	rs3129932	C6orf10 NCBI Gene Pubmed Genecard	32444105	0.1643	0.404	0.04217	2.937e-139	0.0067	7
	rs3129933	C6orf10 NCBI Gene Pubmed Genecard	32444139	0.2178	0.0004232	0.1172	1.761e-19	0.001	73
	rs3129934	C6orf10 NCBI Gene Pubmed Genecard	32444165	0.1082	1	0.05096	7.535e-121	0.005	11
	rs9268402	C6orf10 NCBI Gene Pubmed Genecard	32449331	0.4883	0.0001066	0.8547	0.002597	0.00079	93
	rs9391858	C6orf10 NCBI Gene Pubmed Genecard	32449376	0.1292	0.8962	0.2866	2.035e-17	0.002	40
	rs12528797		32453064	0.1031	0.891	0.4619	0.0003095	0.00051	126
	rs7757831		32453161	0.01955	1	0.07818	5.642e-15	0.00098	80
	rs2894254		32453667	0.1745	0.0001712	0.9318	9.976e-62	0.0022	38
	rs6930777		32459544	0.1022	0.782	0.2634	0.000554	0.00028	182
	rs17423649	HCG23 NCBI Gene Pubmed Genecard	32465111	0.1194	0.5151	0.8151	5.496e-10	0.00032	173
	rs17495612	HCG23 NCBI Gene Pubmed Genecard	32467409	0.1228	0.44	0.8792	5.027e-11	0.00032	171
	rs3129953	HCG23 NCBI Gene Pubmed Genecard	32469799	0.2134	0.0001861	0.3606	3.465e-39	0.0014	57
	rs2076533	BTNL2 NCBI Gene Pubmed Genecard	32471505	0.4773	9.078e-05	0.7952	2.357e-13	0.0023	36
	rs2076530	BTNL2 NCBI Gene Pubmed Genecard	32471794	0.4825	6.126e-05	0.9411	2.652e-12	0.0012	62
	rs10947260	BTNL2 NCBI Gene Pubmed Genecard	32481163	0.05214	0.5142	0.01913	3.847e-10	0.00026	194
	rs3763308	BTNL2 NCBI Gene Pubmed Genecard	32482618	0.02628	1	0.6102	3.463e-20	0.00099	77
	rs6930933		32491388	0.2195	9.67e-06	0.6143	1.023e-35	0.0016	49
	rs2001097		32491836	0.2196	7.241e-06	0.6149	1.508e-35	0.00027	188
	rs9268541		32492505	0.06823	0.7808	0.07867	3.271e-10	0.0005	127
	rs3135377		32493377	0.1477	0.5474	1	1.003e-157	0.015	2
	rs2395167		32496286	0.2203	2.066e-05	0.3454	7.914e-36	0.0004	144
	rs2213580		32496552	0.2191	1.454e-05	0.5294	5.291e-35	0.0019	42
	rs3135366		32496687	0.2189	1.466e-05	0.5704	5.079e-35	0.002	39
	rs9268557		32497283	0.4598	3.295e-08	0.6597	1.074e-45	0.0064	8
	rs9268560		32497490	0.4325	3.412e-07	0.9414	1.497e-34	0.0027	29
	rs3135363		32497626	0.2894	0.003584	0.2042	1.02e-10	0.0016	50
	rs3135342		32504593	0.3258	1.931e-07	0.3506	8.64e-20	0.00077	96
	rs5000563		32512113	0.3256	1.889e-07	0.3981	1.582e-19	0.00061	110
	rs9405035	HLA-DRA NCBI Gene Pubmed Genecard	32515046	0.02478	1	0.0422	0.006669	0.00046	134
	rs3129872	HLA-DRA NCBI Gene Pubmed Genecard	32515131	0.3255	1.889e-07	0.3983	1.309e-19	0.0005	128
	rs3129877	HLA-DRA NCBI Gene Pubmed Genecard	32516575	0.3271	5.598e-08	0.4774	2.264e-20	0.0024	35
	rs3135393	HLA-DRA NCBI Gene Pubmed Genecard	32516820	0.226	0.000447	0.06781	1.649e-32	0.0012	61
	rs3177928	HLA-DRA NCBI Gene Pubmed Genecard	32520413	0.1273	0.4328	0.5617	3.395e-15	0.00098	79
	rs7194	HLA-DRA NCBI Gene Pubmed Genecard	32520458	0.371	5.737e-08	0.8483	2.69e-11	0.003	26
	rs1051336	HLA-DRA NCBI Gene Pubmed Genecard	32520570	0.2256	7.29e-05	0.7618	4.847e-31	0.00072	98
	rs9268831		32535726	0.4677	2.188e-07	0.1425	5.506e-26	0.0043	15
	rs9268856		32537697	0.2814	5.339e-08	0.8082	1.263e-14	0.00044	136
	rs9268861		32537872	0.2416	4.255e-08	0.5398	1.714e-22	0.00063	107
	rs9268862		32538145	0.2808	6.824e-08	0.9609	6.021e-16	0.00051	124
	rs4428528		32538340	0.2539	0.01033	6.914e-05	1.52e-19	0.00039	146
	rs7766843		32538707	0.2815	5.279e-08	0.9227	1.295e-14	0.00037	157
	rs7746922		32538953	0.2881	2.854e-07	1.338e-05	7.869e-11	0.00089	85
	rs9268877		32539125	0.3102	0.02309	0.2936	2.797e-78	0.0042	16
	rs9270986		32682038	0.09403	1	0.0861	3.755e-163	0.014	3
	rs9271208		32686981	0.3067	4.825e-07	0.4763	2.12e-33	0.0014	55
	rs4530903		32689867	0.1024	0.2396	1	0.0623	0.00038	151
	rs9271850		32703038	0.3567	7.25e-07	6.921e-05	5.868e-18	0.00084	89
	rs3129768		32703061	0.1199	0.1691	0.1654	2.179e-118	0.0028	28
	rs9272346	HLA-DQA1 NCBI Gene Pubmed Genecard	32712350	0.2922	0.01043	0.7869	3.433e-151	0.0019	43
	rs9272723	HLA-DQA1 NCBI Gene Pubmed Genecard	32717405	0.2586	0.916	0.0004404	1.352e-154	0.0022	37
	rs9273363		32734250	0.4671	0.005053	0.6336	0	0.053	1
	rs7775228		32766057	0.1039	0.2854	0.1001	5.741e-23	0.00032	172
	rs9469220		32766288	0.3915	7.422e-06	0.8543	6.446e-114	0.0094	6
	rs2647015		32772071	0.08113	0.4315	0.01512	7.14e-30	0.00031	176
	rs2647046		32776314	0.3956	6.873e-09	0.285	0.08167	0.0026	31
	SNP_A-4226034		32778473	0.129	0.1343	0.9368	0.0451	0.0031	25
	rs6936863		32792007	0.3286	1.943e-08	0.1586	1.696e-84	0.0096	5
	rs9461799		32797507	0.3242	0.5447	0.6669	6.273e-43	0.00065	103
	rs9469240		32797979	0.3306	0.9522	0.876	3.693e-42	0.00058	117
	rs2859090		32808811	0.2444	8.891e-06	0.7142	4.815e-07	0.0011	72
	rs2227127	HLA-DQA2 NCBI Gene Pubmed Genecard	32819760	0.3197	0.7114	0.2397	1.802e-45	0.001	74
	rs9276429	HLA-DQA2 NCBI Gene Pubmed Genecard	32820082	0.4821	0.3977	0.7679	1.348e-46	0.0018	44
	rs9276431	HLA-DQA2 NCBI Gene Pubmed Genecard	32820225	0.4821	0.3974	0.7961	6.611e-47	0.00085	87
	rs9276432	HLA-DQA2 NCBI Gene Pubmed Genecard	32820362	0.4817	0.372	0.7962	2.248e-46	0.00076	97
	rs2239800	HLA-DQA2 NCBI Gene Pubmed Genecard	32821245	0.05111	0.6374	1.421e-05	9.219e-23	0.00081	92
	rs9276435	HLA-DQA2 NCBI Gene Pubmed Genecard	32821845	0.218	9.805e-06	0.2436	6.346e-11	0.00094	82
	rs9276440	HLA-DQA2 NCBI Gene Pubmed Genecard	32822761	0.4789	0.2792	1	1.007e-45	0.0013	58
	rs9276448		32823607	0.0806	0.782	0.1818	0.007424	0.0006	111
	rs9276490	MIR3135B NCBI Gene Pubmed Genecard	32826659	0.4774	0.4212	0.9705	1.292e-46	0.0018	45
	rs5014418	MIR3135B NCBI Gene Pubmed Genecard	32827359	0.08271	0.3453	0.4371	0.008196	0.00059	116
	rs7768538	HLA-DQB2 NCBI Gene Pubmed Genecard	32837799	0.4812	0.3978	0.74	2.283e-45	0.00081	91
	rs7453920	HLA-DQB2 NCBI Gene Pubmed Genecard	32837990	0.4823	0.3725	0.7961	9.737e-46	0.0011	66
	rs6902723	HLA-DQB2 NCBI Gene Pubmed Genecard	32839938	0.4157	0.2551	0.8827	2.565e-29	0.00039	145
	rs9296043		32844081	0.336	1	0.7857	6.67e-40	0.00078	94
	rs9296044		32844122	0.3401	0.6855	0.3362	1.552e-40	0.00069	99
	rs1015575		32846093	0.3219	1.873e-05	0.61	1.021e-46	0.004	18
	rs2857212		32848389	0.3144	0.1107	0.6948	9.917e-53	0.0049	12
	rs2621419		32848984	0.3429	0.8791	6.345e-05	0.1176	0.00038	155
	rs2621416		32849846	0.2547	0.3271	0.8821	0.02649	0.001	75
	rs17429127		32859592	0.05009	1	0.05534	1.431e-22	0.00037	160
	rs9276712		32867230	0.04957	1	0.2332	3.381e-22	0.00038	149
	rs2621384		32867251	0.3724	0.04841	0.9692	9.663e-05	0.00026	192
	rs2621330	HLA-DOB NCBI Gene Pubmed Genecard	32889502	0.0496	0.4627	0.01384	6.978e-09	0.00029	179
	rs2070121	HLA-DOB NCBI Gene Pubmed Genecard	32889532	0.06284	0.09977	0.7924	8.65e-11	0.00037	159
	rs17501267	HLA-DOB NCBI Gene Pubmed Genecard	32890127	0.03466	1	0.8341	4.315e-16	0.0012	64
	rs2071474	HLA-DOB NCBI Gene Pubmed Genecard	32890560	0.2279	0.6239	0.9629	1.276e-35	0.0026	30
	rs1894407		32895014	0.3234	0.1442	0.5422	2.355e-07	0.00048	131
	rs9784858		32895153	0.1033	0.1524	1	6.555e-18	0.0011	68
	rs17429458		32895315	0.03445	1	0.8332	8.933e-16	0.00042	140
	rs10484565	TAP2 NCBI Gene Pubmed Genecard	32903010	0.0941	0.1811	0.8931	4.736e-17	0.0011	67
	rs4148873	TAP2 NCBI Gene Pubmed Genecard	32908390	0.1234	0.1037	0.05321	6.614e-25	0.0025	33
	rs241432	TAP2 NCBI Gene Pubmed Genecard	32910181	0.3966	0.311	0.7056	2.41e-06	0.00026	190
	rs241428	TAP2 NCBI Gene Pubmed Genecard	32912048	0.05349	0.07915	0.6245	9.022e-16	0.00047	132
	rs241427	TAP2 NCBI Gene Pubmed Genecard	32912392	0.2774	0.6015	0.4617	4.745e-66	0.0035	22
	rs12529313	TAP1 NCBI Gene Pubmed Genecard	32925108	0.1726	0.9424	0.5841	1.782e-05	0.00034	167
	rs9276832		32940378	0.3372	0.001171	0.2637	0.2969	0.00026	196
	rs3101942	LOC100294145 NCBI Gene Pubmed Genecard	32978035	0.3286	0.653	0.06624	2.238e-73	0.0035	21
	rs17840186	BRD2 NCBI Gene Pubmed Genecard	33046177	0.04312	0.6391	0.07583	7.2e-13	0.00026	195
	rs188245		33063954	0.4938	0.6732	0.6818	2.714e-44	0.0016	48
10	Best: rs7080464 (2)	Gene	131.97-132.00Mb	MAF	HWE(case)	HWE(cont)	p-value	imp.	rank
	rs7080464		131974739	0.01395	1	0.4053	1.04e-27	0.0026	32
	rs7918047		132001099	0.05973	0.5545	0.4041	0.6345	0.00038	152