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Pierre Sacré - Publications ORBI
Grappe, A., Sarma, S. V., Sacré, P., González-Martínez, J., Liégeois-Chauvel, C., & Alario, F.-X. (2019). An intracerebral exploration of functional connectivity during word production. Journal of Computational Neuroscience, 46(1), 125-140.
Peer reviewed (verified by ORBi)
Language is mediated by pathways connecting distant brain regions that have diverse functional roles. For word production, the network includes a ventral pathway, connecting temporal and inferior frontal ...
Sadashivaiah, V., Sacré, P., Guan, Y., Anderson, W. S., & Sarma, S. V. (2018, November). Modeling the interactions between stimulation and physiologically induced APs in a mammalian nerve fiber: dependence on frequency and fiber diameter. Journal of Computational Neuroscience.
Peer reviewed (verified by ORBi)
Electrical stimulation of nerve fibers is used as a therapeutic tool to treat neurophysiological disorders. Despite efforts to model the effects of stimulation, its underlying mechanisms remain unclear ...
Sadashivaiah, V., Sacré, P., Guan, Y., Anderson, W. S., & Sarma, S. V. (2018). Studying the interactions in a mammalian nerve fiber: a functional modeling approach. Proceedings of the 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC).
Peer reviewed
Modern therapeutic interventions are increasingly favoring electrical stimulation to treat neurophysiological dis-orders. These therapies are associated with suboptimal efficacy since most neurostimulation ...
Kerr, M., Sacré, P., Kahn, K., Park, H.-J., Johnson, M., Lee, J., Thompson, S., Bulacio, J., Jones, J., González-Martínez, J., Liégeois-Chauvel, C., Sarma, S., & Gale, J. (2017). The Role of Associative Cortices and Hippocampus during Movement Perturbations. Frontiers in Neural Circuits, 11, 26.
Peer reviewed (verified by ORBi)
Although motor control has been extensively studied, most research involving neural recordings has focused on primary motor cortex, pre-motor cortex, supplementary motor area, and cerebellum. These regions are ...
Breault, M. S., Sacré, P., Johnson, J. J., Kerr, M., Johnson, M. D., Bulacio, J., González-Martínez, J., Sarma, S. V., & Gale, J. T. (2017). Nonmotor regions encode path-related information during movements. 39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC).
Peer reviewed
Sensorimotor control and the involvement of motor brain regions has been extensively studied, but the role nonmotor brain regions play during movements has been overlooked. This is particularly due to the ...
Sacré, P.* , Subramanian, S.* , Kerr, M. S. D., Kahn, K., Johnson, M. A., Bulacio, J., González-Martínez, J. A., Sarma, S. V.* , & Gale, J. T.* . (2017). The influences and neural correlates of past and present during gambling in humans. Scientific Reports, 7, 17111.
Peer reviewed (verified by ORBi)
During financial decision-making tasks, humans often make “rational” decisions, where they maximize expected reward. However, this rationality may compete with a bias that reflects past outcomes. That is, if ...
* These authors have contributed equally to this work.
Sadashivaiah, V., Sacré, P., Guan, Y., Anderson, W. S., & Sarma, S. V. (2017). Modeling electrical stimulation of mammalian nerve fibers: A mechanistic versus probabilistic approach. Proceedings of the 39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC).
Peer reviewed
Electrical neurostimulation is increasingly used over neuropharmacology to treat various diseases. Despite efforts to model the effects of electrical stimulation, its underlying mechanisms remain unclear. This ...
Sacré, P., & Franci, A. (2016). Singularly perturbed phase response curves for relaxation oscillators. Proceedings of the 55th IEEE Conference on Decision and Control (CDC).
Peer reviewed
We exploit a novel geometric method to construct the global isochrones of relaxation oscillators and the associated phase response curve. This method complements the classical infinitesimal (local) phase ...
Sacré, P.* , Kerr, M. S. D.* , Kahn, K., González-Martínez, J., Bulacio, J., Park, H.-J., Johnson, M. A., Thompson, S., Jones, J., Chib, V. S., Gale, J. T.* , & Sarma, S. V.* . (2016). Lucky rhythms in orbitofrontal cortex bias gambling decisions in humans. Scientific Reports, 6, 36206.
Peer reviewed (verified by ORBi)
It is well established that emotions influence our decisions, yet the neural basis of this biasing effect is not well understood. Here we directly recorded local field potentials from the OrbitoFrontal Cortex ...
* These authors have contributed equally to this work.
Sacré, P., Kerr, M. S. D., Subramanian, S., Kahn, K., Gonzalez-Martinez, J., Johnson, M. A., Sarma, S. V., & Gale, J. T. (2016). The precuneus may encode irrationality in human gambling. Podeedings of the 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC).
Peer reviewed
Humans often make irrational decisions, especially psychiatric patients who have dysfunctional cognitive and emotional circuitry. Understanding the neural basis of decision-making is therefore essential ...
Sacré, P., Kerr, M. S. D., Subramanian, S., Kahn, K., Gonzalez-Martinez, J., Johnson, M. A., Gale, J. T., & Sarma, S. V. (2016). Winning versus losing during gambling and its neural correlates. Proceedings of the 2016 Annual Conference on Information Science and Systems (CISS).
Peer reviewed
Humans often make decisions which maximize an internal utility function. For example, humans often maximize their expected reward when gambling and this is considered as a “rational” decision. However, humans ...
Sacré, P., Sarma, S. V., Guan, Y., & Anderson, W. S. (2015). Electrical neurostimulation for chronic pain: on selective relay of sensory neural activities in myelinated nerve fibers. 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC).
Peer reviewed
Chronic pain affects about 100 million adults in the US. Despite their great need, neuropharmacology and neurostimulation therapies for chronic pain have been associated with suboptimal efficacy and limited ...
Sacré, P., & Sepulchre, R. (2014). Sensitivity analysis of circadian entrainment in the space of phase response curves. In V. V., Kulkarni, G.-B., Stan, & K., Raman (Eds.), A Systems Theoretic Approach to Systems and Synthetic Biology II: Analysis and Design of Cellular Systems (pp. 59-81). Netherlands: Springer.
Peer reviewed
Sensitivity analysis is a classical and fundamental tool to evaluate the role of a given parameter in a given system characteristic. Because the phase response curve is a fundamental input–output ...
Sacré, P. (2013). Systems analysis of oscillator models in the space of phase response curves. Unpublished doctoral thesis, University of Liège, ​Liège, ​​Belgium.
Oscillators---whose steady-state behavior is periodic rather than constant---are observed in every field of science. While they have been studied for a long time as closed systems, they are increasingly ...
Mauroy, A., Sacré, P., & Sepulchre, R. (2012). Kick synchronization versus diffusive synchronization. Proceedings of the 51st IEEE Conference on Decision and Control (invited tutorial session) (pp. 7171-7183).
Peer reviewed
The paper provides an introductory discussion about two fundamental models of oscillator synchronization: the (continuous-time) diffusive model, that dominates the mathematical literature on synchronization ...
Sacré, P., & Sepulchre, R. (2011). Matching an oscillator model to a phase response curve. Proceedings of the Joint 50th IEEE Conference on Decision and Control and European Control Conference (pp. 3909-3914).
Peer reviewed
The Phase Response Curve (PRC) has proven a useful tool for the reduction of complex oscillator models. It is also an information often experimentally available to the biologist. This paper introduces a ...
Sacré, P., & Sepulchre, R. (2011, May 23). Sensitivity analysis of phase response curves. Paper presented at SIAM Conference on Applications of Dynamical Systems, Snowbird, UT.
The Phase Response Curve (PRC) has proven a useful tool for the reduction of complex oscillator models to one-dimensional phase models. We introduce the sensitivity analysis of this important mathematical ...
Hafner, M., Sacré, P., Symul, L., Sepulchre, R., & Koeppl, H. (2010). Multiple feedback loops in circadian cycles: robustness and entrainment as selection criteria. Proceedings of the Seventh International Workshop on Computational Systems Biology, WCSB 2010.
Peer reviewed
This paper discusses the contribution of an additional feedback loop to the entrainment and the robustness of a circadian system. To quantify robustness, we perform a global analysis of the system's parameter ...
Efimov, D., Sacré, P., & Sepulchre, R. (2009). Controlling the phase of an oscillator: a phase response curve approach. Proceedings of the Joint 48th IEEE Conference on Decision and Control and 28th Chinese Control Conference (pp. 7692–7697).
Peer reviewed
The paper discusses elementary control strategies to control the phase of an oscillator. Both feedforward and feedback (P and PI) control laws are designed based on the phase response curve (PRC) calculated ...
Sacré, P. (2008). Dynamique non-linéaire de la molécule d’ADN : modélisation de sa dénaturation. Unpublished master thesis, Université de Liège, ​Liège, ​​Belgique.
L’ADN est une molécule fabuleuse et essentielle dont la structure et la fonction sont en étroite relation. Elle est un centre d’intérêt important à la fois pour les biologistes, les chimistes et les physiciens ...