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Samuel Hiard - Publications ORBI
Hiard, S. (2013). Trimming the complexity of Ranking by Pairwise Comparison. Unpublished doctoral thesis, Université de Liège, ​Liège, ​​Belgique.
In computer science research, and more specifically in bioinformatics, the size of databases never stops to increase. This can be an issue when trying to answer questions that imply algorithms in nonlinear ...
Hiard, S., Geurts, P., & Wehenkel, L. (2012). Comparator selection for RPC with many labels. ECAI 2012 : 20th European Conference on Artificial Intelligence : 27-31 August 2012, Montpellier, France (pp. 408-413). Amsterdam, Netherlands: IOS Press.
Peer reviewed
The Ranking by Pairwise Comparison algorithm (RPC) is a well established label ranking method. However, its complexity is of O(N²) in the number N of labels. We present algorithms for selection, before model ...
Hiard, S., & Wehenkel, L. (2011). Using Class-probability Models instead of Hard Classifiers as Base Learners in the Ranking by Pairwise Comparison Algorithm. In S., Thatcher (Ed.), ICMLC 2011 3rd International Conference on Machine Learning and Computing Volume 1 (pp. 218-222). Chengdu, China: IEEE.
In the field of Preference Learning, the Ranking by Pairwise Comparison algorithm (RPC) consists of using the learning sample to derive pairwise comparators for each possible pair of class labels, and then ...
Hiard, S., Charlier, C., Coppieters, W., Georges, M., & Baurain, D. (2010). Patrocles: a database of polymorphic miRNA-mediated gene regulation in vertebrates. Nucleic Acids Research, 38(Database), 640-D651.
Peer reviewed (verified by ORBi)
The Patrocles database (http://www.patrocles.org/) compiles DNA sequence polymorphisms (DSPs) that are predicted to perturb miRNA-mediated gene regulation. Distinctive features include: (i) the coverage of ...
Hiard, S., Rigali, S., Colson, S., Marée, R., & Wehenkel, L. (2007, November 12). PREDetector : Prokaryotic Regulatory Element Detector. Poster session presented at Benelux Bioinformatics Conference 2007, Leuven, Belgium.
Background: In the post-genomic area, in silico predictions of regulatory networks are considered as a powerful approach to decipher and understand biological pathways within prokaryotic cells. The emergence ...
Hiard, S., Tordoir, X., Coppieters, W., Charlier, C., & Georges, M. (2007, November 12). Compiling polymorphic miRNA-target interactions: the Patrocles database. Poster session presented at Benelux Bioinformatics Conference 2007, Leuven, Belgium.
Using positional cloning, we have recently identified the mutation responsible for muscular phenotype of the Texel sheep. It is located in the 3’UTR of the GDF8 gene - a known developmental repressor of ...
Huynh-Thu, V. A., Hiard, S., Geurts, P., Muller, M., Struman, I., Martial, J., & Wehenkel, L. (2007, September). Detection of micro-RNA/gene interactions involved in angiogenesis using machine learning techniques. Poster session presented at Workshop on Machine Learning in Systems Biology (MLSB07), Evry, France.
Motivation: Angiogenesis is the process responsible for the growth of new blood vessels from existing ones. It is also associated with the development of cancer, as tumors need to be irrigated by blood vessels ...
Hiard, S., Marée, R., Colson, S., Hoskisson, P. A., Titgemeyer, F., van Wezel, G. P., Joris, B., Wehenkel, L., & Rigali, S. (2007). PREDetector: A new tool to identify regulatory elements in bacterial genomes. Biochemical and Biophysical Research Communications, 357(4), 861-864.
Peer reviewed (verified by ORBi)
In the post-genomic area, the prediction of transcription factor regulons by position weight matrix-based programmes is a powerful approach to decipher biological pathways and to modelize regulatory networks ...
Hiard, S., Rigali, S., Colson, S., Marée, R., & Wehenkel, L. (2007, February 15). PREDetector : Prokaryotic Regulatory Element Detector. Poster session presented at Bioinformatics and Modeling : From genomes to network, Liège, Belgium.
Background: In the post-genomic area, in silico predictions of regulatory networks are considered as a powerful approach to decipher and understand biological pathways within prokaryotic cells. The emergence ...
Hiard, S., Tordoir, X., Coppieters, W., Charlier, C., & Georges, M. (2007, February 15). Compiling polymorphic miRNA-target interactions: the Patrocles database. Poster session presented at Bioinformatics and Modeling : From genomes to network, Liège, Belgium.
Using positional cloning, we have recently identified the mutation responsible for muscular phenotype of the Texel sheep. It is located in the 3’UTR of the GDF8 gene - a known developmental repressor of ...
Georges, M., Clop, A., Marcq, F., Takeda, H., Pirottin, D., Tordoir, X., Hiard, S., Bibé, B., Bouix, J., Caiment, F., Eychenne, F., Larzul, C., Laville, E., Meish, F., Milenkovic, D., Tobin, J., & Charlier, C. (2006). Polymorphic miRNA-target interactions : A Novel Source of Phenotypic Variation. Cold Spring Harbor Symposia on Quantitative Biology, 71, 343-350.
Peer reviewed (verified by ORBi)
Studying the muscular hypertrophy of Texel sheep by forward genetics, we have identified an A-to-G transition in the 3'UTRof the GDF8 gene that reveals an illegitimate target site for microRNAs miR-1 and miR ...
Takeda, H., Caiment, F., Smit, M., Hiard, S., Tordoir, X., Cockett, N., Georges, M., & Charlier, C. (2006). The callipyge mutation enhances bidirectional long-range DLK1-GTL2 intergenic transcription in cis. Proceedings of the National Academy of Sciences USA, 103(21), 8119-8124.
Peer reviewed (verified by ORBi)
The callipyge mutation (CLPG) is an A to G transition that affects a muscle-specific long-range control element located in the middle of the 90-kb DLK1-GTL2 intergenic (IG) region. It causes ectopic expression ...
Hiard, S., Rigali, S., Colson, S., Marée, R., & Wehenkel, L. (2006, May 17). PreDetector : Prokaryotic Regulatory Element Detector. Poster session presented at 10th Bioforum, Liège, Belgium.
PreDetector is a stand-alone software, written in java. Its final aim is to predict regulatory sites for prokaryotic species. It comprises two functionalities. The first one is very similar to Target ...